Taddeo di Bartolo was born in Siena. Much of his early work was in Pisa, where he was responsible for the frescoes of Paradise and Hell in the Cathedral there, and for paintings in the Palazzo Pubblico and the church of San Francesco. At the Collegiata di San Gimignano, Taddeo painted a fresco depicting the Last Judgment. A painting by Taddeo of Saint Gimignano holding the town in his lap (c. 1391) may be seen at the Museo Civico there. A triptcyh of the Virgin and Child with St John the Baptist and St Andrew, painted around 1395, is on display at the Museum of Fine Arts in Budapest. A massive triptych, Assumption of the Virgin, painted in 1401, is situated in the 16th century Duomo of Santa Maria dell'Assunta at Montepulciano. Taddeo's Madonna with Child, Four Angels and Saint John the Baptist and Saint Andrew may be seen in the Oratory of the Company of Saint Catherine of the Night, at Santa Maria della Scala, Siena. He also painted allegories and figures from Roman history (1413–14), and the Funeral of the Virgin (1409) at the Palazzo Pubblico in Siena. A Madonna and Child (c. 1400), painted with tempera and oil on a panel, is located in the Wadsworth Atheneum. Another Madonna and Child is in the collection of the Museum of Fine Arts, San Francisco, California, and yet another Madonna and Child is housed in the Musée du Petit Palais, Avignon, France. Taddeo di Bartolo died at Siena at about age 60.